JO1 Members Profile (Updated!)

Keywords: ANTISYNTHETASE ANTIBODIES; INTERSTITIAL LUNG DISEASE; Jo1; POLYMYOSITIS; Ro52. Objective: Rituximab RTX has been used successfully for the treatment of severe Jo1 antibody-associated antisynthetase syndrome. Tsurubo Shion: 178 cm 5'10'' 5. Conclusion: RTX is effective in the treatment of severe forms of Jo1 antisynthetase syndrome. It can be considered a specific marker of IIM, predominantly found in 20-30% of patients with PM and in the 60-70% of those with interstitial pulmonary fibrosis. Ohira Shosei: 176 cm 5'9'' 6. One patient treated with RTX died of pneumonia. Krause, MD, Department of Medical Informatics, Biometry and Epidemiology, Ruhr University Bochum; C. Methods: There were 61 patients with Jo1 antisynthetase syndrome identified; 18 of these received RTX. Targoff I: Autoantibodies in polymyositis. Kinjo Sukai: 178 cm 5'10'' 4. JO1 debuted on March 4, 2020 with eleven members: Issei Mamehara, Ren Kawashiri, Takumi Kawanishi, Shosei Ohira, Shion Tsurubo, Ruki Shiroiwa, Keigo Sato, Syoya Kimata, Junki Kono, Sukai Kinjo and Sho Yonashiro. JO1 MEMBERS, BIRTHDAYS, AND POSITIONS Yonashiro Sho Oct 25, 1995 leader, main vocalist 2. FNC trainee and used to hang around with him a lot. Shiroiwa Ruki: 175 cm 5'9'' 7. Jo 1 antibodies in patients with polymyositis bind to conformational epitopes of the enzyme protein and inhibit its catalytic activity in vitro. Mamehara Issei May 30, 2002 main dancer, rapper, vocalist, maknae JO1 HEIGHT RANKING 1. Louis, Mosby-Year Book, 2001, pp 65. Kawanishi Takumi: 170 cm 5'7'' SOCIAL MEDIA Youtube: Official Website: Instagram: Twitter:. Kimata Syoya Apr 5, 2000 lead dancer, lead rapper, vocalist 8. These antibodies are also found in DM, although less frequently than in PM, and are rare in children with PM or DM and in other connective tissue diseases. Shiroiwa Ruki Nov 19, 1997 vocalist, rapper 4. Max, MD, Department of Internal Medicine V, University of Heidelberg; H. Ohira Shosei Apr 13, 2000 lead dancer, vocalist 9. Kawashiri Ren: 173 cm 5'8'' 9. The remaining 17 patients and 30 out of 43 patients who were treated with conventional immunosuppressive IS drugs were followed for a mean of 35 months and 84 months, respectively. The detection of this antibody is particularly useful in diagnosis and classification of IIM. Leff R, Sherman J, Plotz P: Chapter 65: Inflammatory muscle diseases. In our retrospective study, the presence of high anti-Ro52 antibody concentrations predicts severe acute-onset ILD and nonresponse to IS drugs. JO1 Members Profile: JO1 Facts JO1 is an eleven-member Japanese boy group formed by the top contestants of Produce 101 Japan under LAPONE ENTERTAINMENT. Tsurubo Shion Dec 11, 2000 main rapper 11. Bauhammer, MD, ACURA Centre for Rheumatic Diseases; N. Mamehara Issei: 173 cm 5'8'' 10. Unlike other Produce 101 groups that disband after their contract expires, JO1 is intended to be a permanent group. Anti-Jo-1 antibody is a myositis specific autoantibody most commonly found in patients with idiopathic inflammatory myopathies IIM. In Clinical Immunology Principles and Practice, Second edition. Kinjo Sukai May 6, 2000 lead vocalist, rapper 10. The Members consist of Yonashiro Sho, Kawashiri Ren, Shiroiwa Ruki, Kono Junki, Sato Keigo, Kawanishi Takumi, Kimata Syoya, Ohira Shosei, Kinjo Sukai, Tsurubo Shion and Mamehara Issei. The antibodies occur in up to 50% of patients with interstitial pulmonary fibrosis and symmetrical polyarthritis. Evaluating patients with signs and symptoms compatible with a connective tissue disease, especially those patients with muscle pain and limb weakness, concomitant pulmonary signs and symptoms, Raynaud phenomenon, and arthritis Testing for antibodies to Jo 1 is not useful in patients with a negative test for antinuclear antibodies Testing Algorithm Jo 1 histidyl tRNA synthetase is a member of the amino acyl-tRNA synthetase family of enzymes found in all nucleated cells. Blank, MD, Department of Internal Medicine V, University of Heidelberg; R. The aim of this retrospective study was to evaluate the effect of RTX in severe Jo1 antisynthetase syndrome and determine predictive factors for response. Rheum Dis Clin North Am 1992;18:455 2. Moreover, anti-Jo-1 serum levels strongly correlate with disease activity representing a good marker for disease monitoring. One patient was lost to followup. Edited by R Rich, T Fleisher, W Shearer, B Kotzin, et al. Kono Junki Jan 20, 1998 main vocalist 5. Sato Keigo: 181 cm 5'11'' 2. Wagner, MD, Department of Pneumology, Klinikum LΓΆwenstein; D. Yonashiro Sho: 180 cm 5'11'' 3. This antibody is directed against the histidyl-tRNA synthetase which catalyses the binding of the histidine to its cognate tRNA during protein synthesis. Kimata Syoya: 171 cm 5'7'' 11. Kawashiri Ren Mar 2, 1997 main dancer, lead vocalist, sub rapper 3. In contrast to conventional IS, RTX is equally effective in patients with Jo1 antisynthetase syndrome, independent of their anti-Ro52 antibody status. ELISA, CIE and immunoblotting are highly specific and sensitive techniques for testing anti-Jo-1 antibodies. Sixteen out of 18 patients 89% showed a fast and marked response to RTX. Kawanishi Takumi Jun 23, 1999 lead dancer, lead vocalist 7. Lorenz, MD, ACURA Centre for Rheumatic Diseases, and Department of Internal Medicine V, University of Heidelberg; U. Sato Keigo Jul 29, 1998 lead dancer, lead vocalist, sub rapper 6. 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